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  3. \u56fd\u5bb6\u81ea\u7136\u79d1\u5b66\u57fa\u91d1\u9762\u4e0a\u9879\u76ee\uff1a\u767d\u85dc\u82a6\u9187\u901a\u8fc7miR-330\u9776\u5411\u8c03\u63a7MRP1\u8bf1\u5bfc\u9f3b\u54bd\u764c\u653e\u5c04\u589e\u654f\u7684\u7814\u7a76\uff0c2013-01\u81f32016-12\uff0c68\u4e07\u5143\uff0c\u4e3b\u6301\u3002<\/li>\n\n\n\n
  4. \u5e7f\u4e1c\u7701\u81ea\u7136\u79d1\u5b66\u57fa\u91d1\u9762\u4e0a\u9879\u76ee\uff1a\u4e00\u77f3\u4e8c\u9e1f\uff1a\u9632\u5df1\u8bfa\u6797\u78b1\u901a\u8fc7\u63d0\u5347\u6811\u7a81\u72b6\u7ec6\u80de\u4e0e\u80bf\u7624\u7ec6\u80de\u6297\u539f\u63d0\u5448\u80fd\u529b\u589e\u5f3a\u6297\u80bf\u7624\u514d\u75ab\uff0c2025-01\u81f32027-12\uff0c10\u4e07\u5143\uff0c\u4e3b\u6301\u3002<\/li>\n\n\n\n
  5. \u5e7f\u4e1c\u7701\u81ea\u7136\u79d1\u5b66\u57fa\u91d1\u9762\u4e0a\u9879\u76ee\uff1aCirc-EphB4\u5728\u809d\u7ec6\u80de\u764c\u4e2d\u7684\u4f5c\u7528\u53ca\u5176\u5206\u5b50\u673a\u5236\uff0c2017-10\u81f32020-09,10\u4e07\u5143\uff0c\u4e3b\u6301\u3002<\/li>\n\n\n\n
  6. \u5e7f\u4e1c\u7701\u81ea\u7136\u79d1\u5b66\u57fa\u91d1\u9762\u4e0a\u9879\u76ee\uff1amiR-30a\u9776\u5411\u8c03\u63a7USP22\u6291\u5236\u9f3b\u54bd\u764c\u7ec6\u80de\u7ec6\u80de\u751f\u957f\u589e\u6b96\u7684\u7814\u7a76\uff0c2012-10\u81f32015-09\uff0c3\u4e07\u5143\uff0c\u4e3b\u6301\u3002<\/li>\n\n\n\n
  7. \u5e7f\u5dde\u5e02\u79d1\u6280\u8ba1\u5212\u9879\u76ee\uff1a\u57fa\u4e8eDC\u6297\u539f\u5904\u7406\u8fc7\u7a0b\u7814\u7a76\u9632\u5df1\u9ec4\u82aa\u65b9\u5bf9\u80bf\u7624\u514d\u75ab\u6740\u4f24\u7684\u589e\u6548\u4f5c\u7528\uff0c2022-04\u6708\u81f3 2024-03\u6708\uff0c10\u4e07\u5143\uff0c\u4e3b\u6301\u3002<\/li>\n\n\n\n
  8. \u6559\u80b2\u90e8\u535a\u58eb\u70b9\u57fa\u91d1\uff1a\u767d\u85dc\u82a6\u9187\u5bf9\u9f3b\u54bd\u764c\u653e\u5c04\u589e\u654f\u7684\u673a\u5236\u7814\u7a76\uff0c2012-01\u81f32015-12\uff0c4\u4e07\u5143\uff0c\u4e3b\u6301<\/li>\n\n\n\n
  9. \u5e7f\u5dde\u4e2d\u533b\u836f\u5927\u5b662017\u5e74\u5ea6\u201c\u9ad8\u6c34\u5e73\u5927\u5b66\u201d\u5efa\u8bbe\u9879\u76ee\uff1a\u767d\u85dc\u82a6\u9187\u4e0a\u8c03circEphB4\u6291\u5236\u809d\u764c\u589e\u6b96\u548c\u8f6c\u79fb\u7684\u7814\u7a76\uff0c2017-01\u81f32018-12\uff0c20\u4e07\u5143\uff0c\u4e3b\u6301\u3002<\/li>\n\n\n\n
  10. \u5e7f\u4e1c\u7701\u666e\u901a\u9ad8\u6821\u7279\u8272\u521b\u65b0\u9879\u76ee\uff08\u81ea\u7136\u79d1\u5b66\uff09\uff1aCirc-EphB4\u901a\u8fc7\u4e0b\u8c03CCL20\u6291\u5236\u809d\u7ec6\u80de\u764c\u589e\u6b96\u548c\u8f6c\u79fb\u7684\u7814\u7a76\uff0c2017-01\u81f32019-12\uff0c10\u4e07\u5143\uff0c\u4e3b\u6301\u3002<\/li>\n<\/ol>\n\n\n\n

    \u8fd1\u5e74\u53d1\u8868\u8bba\u6587<\/strong>\u60c5\u51b5\uff1a<\/strong><\/p>\n\n\n\n

    1\u3001Song Y#<\/sup>, Jiang Y#<\/sup>, Guan J#<\/sup>, Jiang J, Xu M, Zhong X, He L, Ren Z, Liao Y, Liu F, Jiang Y, Hu S, Guo W, Zhao T, Liu X, Gu J, Shi Y, Luo H*, Wang K*, Xiao J<\/strong>*. Fangchinoline-mediated autophagy inhibition amplifies antigen presentation and PD-1 blockade efficacy in lung cancer. Acta Pharmacol Sin. <\/em><\/strong>2025 Oct;46(10):2751-2764.<\/p>\n\n\n\n

    2\u3001He LN#<\/sup>, Liu YJ#<\/sup>, Jiang JB#<\/sup>, Wang DY, Li YL, Zeng SJ, Guo Z, Yao PY, Lin ZC, Lv SX, Liu XY, Guo W, Liu F, Du BY, Zhao TX*, Xiao JY<\/strong>*, Shi YF*, Wang K*. Tetrandrine augments melanoma cell immunogenicity via dual inhibition of autophagic flux and proteasomal activity enhancing MHC-I presentation. Acta Pharmacol Sin. <\/em><\/strong>2025 Jul;46(7):2056-2072. <\/p>\n\n\n\n

    3\u3001Zhan Y#<\/sup>, Chen Q#<\/sup>, Song Y#<\/sup>, Wei X, Zhao T, Chen B, Li C, Zhang W, Jiang Y, Tan Y, Du B, Xiao J<\/strong>*, Wang K*. Berbamine Hydrochloride inhibits lysosomal acidification by activating Nox2 to potentiate chemotherapy-induced apoptosis via the ROS-MAPK pathway in human lung carcinoma cells. Cell Biol Toxicol<\/em><\/strong>.<\/em> 2023 Aug;39(4):1297-1317. <\/p>\n\n\n\n

    4\u3001Ren Z#, Song Y#, Xian J#, Liao Y, Zhan Y, Zhao T, Wang H, Jiang J, Xu M, Jiang Y, Liu X, Wei X*, Wang K*, Xiao J<\/strong>*. Identification of Fangchinoline as a novel autophagy inhibitor with an adjuvant of chemotherapy against lung cancer. \u00a0Toxicol Appl Pharmacol<\/em><\/strong>.<\/em> 2023 Oct 15;477:116679. <\/p>\n\n\n\n

    5\u3001Chen Q#<\/sup>, Liao Y#<\/sup>, Liu Y#<\/sup>, Song Y, Jiang J, Zhang Z, Li A, Zheng M, Chen X, Zhao T, Gu J, Tan Y, Liu X, Jiang Y, Wang K, Yi H*, Xiao J<\/strong>*, Hu S*. Identification of Fangjihuangqi Decoction as a late-stage autophagy inhibitor with an adjuvant anti-tumor effect against non-small cell lung cancer. Chin Med<\/em><\/strong>. <\/em>2023 Jun 7;18(1):68. <\/p>\n\n\n\n

    6\u3001Chen B#<\/sup>, Song Y#<\/sup>, Zhan Y#<\/sup>, Zhou S, Ke J, Ao W, Zhang Y, Liang Q, He M, Li S, Xie F, Huang H, Chan WN, Cheung AHK, Ma BBY, Kang W, To KF*, Xiao J<\/strong>*.Fangchinoline inhibits non-small cell lung cancer metastasis by reversing epithelial-mesenchymal transition and suppressing the cytosolic ROS-related Akt-mTOR signaling pathway. Cancer Lett<\/em><\/strong>. <\/em>2022 Sep 1;543:215783. <\/p>\n\n\n\n

    7\u3001Chen J#<\/sup>, Hu S#<\/sup>, Wang H#<\/sup>, Zhao T, Song Y, Zhong X, Luo Q, Xu M, He L, Chen Q, Du B*, Xiao J<\/strong>*, Wang K*. Integrated analysis reveals the pivotal interactions between immune cells in the melanoma tumor microenvironment. Sci Rep<\/em><\/strong>.<\/em> 2022 Jun 16;12(1):10040. <\/p>\n\n\n\n

    8\u3001Lai Y#<\/sup>, Han T#<\/sup>, Lao Z#<\/sup>, Li G, Xiao J<\/strong>*, Liu X*. Phillyrin for COVID-19 and Influenza Co-infection: A Potential Therapeutic Strategy Targeting Host Based on Bioinformatics Analysis. Front Pharmacol<\/em><\/strong>.<\/em> 2021 Nov 4;12:754241.<\/p>\n\n\n\n

    9\u3001Wang K#<\/sup>, Gong Q#<\/sup>, Zhan Y#<\/sup>, Chen B, Yin T, Lu Y, Zhang Y, Wang H, Ke J, Du B, Liu X*, Xiao J<\/strong>*. Blockage of Autophagic Flux and Induction of Mitochondria Fragmentation by Paroxetine Hydrochloride in Lung Cancer Cells Promotes Apoptosis via the ROS-MAPK Pathway. Front Cell Dev Biol<\/em><\/strong>.<\/em> 2020 Jan 22;7:397.<\/p>\n\n\n\n

    10\u3001Wang K#<\/sup>, Zhan Y#<\/sup>, Chen B#<\/sup>, Lu Y, Yin T, Zhou S, Zhang W, Liu X, Du B, Wei X*, Xiao J<\/strong>*. Tubeimoside I-induced lung cancer cell death and the underlying crosstalk between lysosomes and mitochondria. Cell Death Dis<\/em><\/strong>.<\/em> 2020 Aug 26;11(8):708.<\/p>\n\n\n\n

    11\u3001Wang K#<\/sup>, Liu X#<\/sup>, Liu Q#<\/sup>, Ho IH, Wei X, Yin T, Zhan Y, Zhang W, Zhang W, Chen B, Gu J, Tan Y, Zhang L, Chan MT, Wu WK*, Du B*, Xiao J<\/strong>*. Hederagenin potentiated cisplatin- and paclitaxel-mediated cytotoxicity by impairing autophagy in lung cancer cells. Cell Death Dis<\/em><\/strong>. <\/em>2020 Aug 13;11(8):611. <\/p>\n\n\n\n

    \u5b66\u672f\u517c\u804c<\/strong>\uff1a<\/strong><\/p>\n\n\n\n

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    \u884c\u653f\u804c\u52a1<\/strong>\uff1a<\/strong><\/p>\n<\/div><\/div>\n\n\n\n

    \u673a\u6784<\/strong><\/td>\u804c\u52a1<\/strong><\/td><\/tr>
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    \u8054\u7cfb\u65b9\u5f0f\uff1a<\/strong><\/p>\n\n\n\n

    \u90ae\u7bb1<\/strong><\/td>jianyongxiao@gzucm.edu.cn<\/td><\/tr>
    \u624b\u673a<\/strong><\/td>18902383596<\/td><\/tr>
    \u4e2a\u4eba\u4e3b\u9875<\/strong><\/td>http:\/\/xiaojy.oncolab.cn<\/td><\/tr>
    \u5fae\u4fe1\u516c\u4f17\u53f7<\/strong><\/td>OncoLab<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n
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    \"\"<\/figure><\/div>\n\n\n

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